2.3 Diagnosis The diagnosis is made from history of exposure and clinicalįeatures: tingling and burning sensation of mouth and throat,Įxcessive salivation, gastroenteritis, cardiac dysrhythmias,Īconitine and other alkaloids can be identified in gastricĬontents or in the plant (e.g. Loss ofĬonsciousness and dysarthria may occur. Paraesthesia that can spread over the entire body. Intoxication may first cause excitement and then paralysis of Poisoning may resolve in 24 to 48 hours, but the neurologicalĮffects (especially generalized weakness) may persist forĭisorders of the thermal regulation centre may occur. Occur within the first 24 hours of poisoning, ECGĪbnormalities may persist for several days. Supraventricular tachycardia, ventricular tachycardia and Severe poisoning is characterized by cardiac effects:Ĭonduction abnormalities, with sinus bradycardia, Salivation, nausea, vomiting, and diarrhoea. Tingling of the mouth and tongue, followed within hours by 2.2 Summary of clinical effects The first symptoms of poisoning appear rapidly: numbness and Respiratory paralysis andĬonvulsions may occur. The main risks are cardiovascular collapse and ventricularĪrrythmias, as well as vomiting and diarrhoea leading toĭehydration and hypotension. Nervous systems (bulbar paralysis), and also the SUMMARY 2.1 Main risks and target organs The main target organs are the cardiovascular and central 1979) Haba de lobo (Argentina) Kurt (Turkey) Larkspur (USA, UK) Monkshood (USA, UK) Raiz del diablo (Argentina) Staggerweed (USA, UK) (Hardin, 1974) Wolfsbane (USA, UK) 2. Aconitum pyramidale Mill (Dewit, 1962) Aconitum reclinatum Gray (white flowers) Aconitum uncinatum (blue flowers) Aconitysat Anapello (Italy) Anapelo (Spain, Argentina, Uruguay) Capilla de mono (Argentina) Delfinium (USA), Delphinium (UK) Espora (Brazil) Espora-de-jardin (Brazil) Esporiaha-de-jardin (Brazil) (Schvartsman, S. 1.2 Family Leguminosae 1.3 Common name(s) Aconite "feroz" (Argentina, Uruguay) Aconite "maralobo" (Argentina) Aconite "saludable" (Argentina) Aconite (Spain, Argentina, Uruguay) Aconite (USA, UK) Aconite de flor grande (Argentina, Uruguay) Aconite napelo (Spain) Aconitum carmichaelii Aconitum columbiatum Nutt Aconitum japonicum Aconitum napellus L. NAME 1.1 Scientific name Aconitum napellus spp. AUTHOR(S), REVIEWER(S), DATE(S) (INCLUDING UPDATES), COMPLETE ADDRESS(ES)ġ. TOXICOLOGICAL/TOXINOLOGICAL ANALYSES AND BIOMEDICAL INVESTIGATIONSĨ.1.2 Storage of laboratory samples and specimensĨ.1.3 Transport of laboratory samples and specimensĨ.2 Toxicological Analyses and Their InterpretationĨ.2.1 Tests on toxic ingredient(s) of materialĨ.2.1.2 Advanced Qualitative Confirmation Test(s)Ĩ.2.2.2 Advanced Qualitative Confirmation Test(s)Ĩ.2.3 Interpretation of toxicological analysesĨ.3 Biomedical investigations and their interpretationĨ.3.4 Interpretation of biomedical investigationsĨ.4 Other biomedical (diagnostic) investigations and their interpretationĨ.5 Overall Interpretation of all toxicological analyses and toxicological investigationsĩ.4 Systematic description of clinical effectsĩ.4.9 Eye, ears, nose, throat: local effectsĩ.4.12.2 Fluid and electrolyte disturbancesġ0.2 Relevant laboratory analyses and other investigationsġ0.2.3 Toxicological/toxinological analysisġ0.3 Life supportive procedures and symptomatic treatmentġ2.1 Availability of antidotes/antitoxinsġ4. NAMEĢ.4 First-aid measures and management principlesģ.3.2 Description, chemical structure, stabilityģ.3.3 Other physico-chemical characteristicsĦ.3 Biological half-life by route of exposureĨ.
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